Flight schedule from Des Moines International Airport
| Flight | Flight days | Departure | Arrival | Flight time | Airlines | Price | ||
|---|---|---|---|---|---|---|---|---|
| AA1985 | Des Moines — Charlotte | mon, wed, sun | 13:52 | 17:15 | 2h 23m | American Eagle | search | |
| AA1985 | Des Moines — Charlotte | tue, wed | 14:00 | 17:23 | 2h 23m | American Eagle | search | |
| AA1985 | Des Moines — Charlotte | mon, thu, fri, sat, sun | 14:02 | 17:25 | 2h 23m | American Eagle | search | |
| AA1312 | Des Moines — Chicago | daily | 05:00 | 06:29 | 1h 29m | American Eagle | search | |
| WN2131 | Des Moines — Chicago | tue | 15:15 | 16:35 | 1h 20m | Southwest Airlines | search | |
| AA4923 | Des Moines — Chicago | fri | 19:44 | 21:19 | 1h 35m | SkyWest Airlines | search | |
| WN1251 | Des Moines — Denver | mon | 06:25 | 07:30 | 2h 5m | Southwest Airlines | search | |
| WN1251 | Des Moines — Denver | tue, wed | 08:35 | 09:45 | 2h 10m | Southwest Airlines | search | |
| DL4647 | Des Moines — Detroit | fri, sun | 17:43 | 20:34 | 1h 51m | Delta Connection | search | |
| DL5345 | Des Moines — Detroit | mon, tue, wed, fri, sun | 17:47 | 20:32 | 1h 45m | Delta Connection | search | |
| G4447 | Des Moines — Las Vegas | thu, sun | 07:30 | 08:49 | 3h 19m | Allegiant Air | search | |
| WN3804 | Des Moines — Las Vegas | sat | 18:15 | 19:35 | 3h 20m | Southwest Airlines | search | |
| AA3538 | Des Moines — Miami | mon | 06:00 | 10:20 | 3h 20m | American Eagle | search | |
| AA3538 | Des Moines — Miami | fri | 06:35 | 10:57 | 3h 22m | American Eagle | search | |
| AA3538 | Des Moines — Miami | tue, wed, sat, sun | 07:00 | 11:20 | 3h 20m | American Eagle | search | |
| G4478 | Des Moines — Phoenix | wed | 07:00 | 08:08 | 3h 8m | Allegiant Air | search | |
| WN2497 | Des Moines — Phoenix | tue, wed | 13:55 | 15:00 | 3h 5m | Southwest Airlines | search | |
| WN2497 | Des Moines — Phoenix | mon, thu, fri | 14:15 | 15:20 | 3h 5m | Southwest Airlines | search | |
| WN2497 | Des Moines — Phoenix | thu, fri | 14:15 | 16:20 | 3h 5m | Southwest Airlines | search | |
| AA2651 | Des Moines — Phoenix | mon, tue, wed, thu, sat, sun | 14:28 | 15:39 | 3h 11m | American Eagle | search | |
| AA2029 | Des Moines — Phoenix | tue, wed, thu | 14:38 | 15:47 | 3h 9m | American Eagle | search | |
| G4478 | Des Moines — Phoenix | mon, fri | 15:51 | 16:59 | 3h 8m | Allegiant Air | search | |
| G4478 | Des Moines — Phoenix | mon | 15:56 | 17:04 | 3h 8m | Allegiant Air | search | |
| G4478 | Des Moines — Phoenix | sat | 16:02 | 17:10 | 3h 8m | Allegiant Air | search | |
| WN2497 | Des Moines — Phoenix | sat | 19:55 | 22:00 | 3h 5m | Southwest Airlines | search | |
| G4476 | Des Moines — Punta Gorda | sat | 07:00 | 10:59 | 2h 59m | Allegiant Air | search | |
| G4476 | Des Moines — Punta Gorda | sat | 07:30 | 11:29 | 2h 59m | Allegiant Air | search | |
| G4476 | Des Moines — Punta Gorda | sat | 08:30 | 12:29 | 2h 59m | Allegiant Air | search | |
| G4433 | Des Moines — Sarasota | tue | 10:00 | 13:45 | 2h 45m | Allegiant Air | search | |
| G42703 | Des Moines — Tampa | sat | 18:14 | 21:58 | 2h 44m | Allegiant Air | search | |
| G41028 | Des Moines — Tampa | thu, sun | 19:53 | 23:36 | 2h 43m | Allegiant Air | search | |
| AA5414 | Des Moines — Washington | tue, wed | 06:00 | 09:29 | 2h 29m | American Eagle | search | |
| AA5414 | Des Moines — Washington | sat | 07:28 | 10:59 | 2h 31m | American Eagle | search | |