Flight schedule from Owen Roberts International Airport
| Flight | Flight days | Departure | Arrival | Flight time | Airlines | Price | ||
|---|---|---|---|---|---|---|---|---|
| DL2512 | Grand Cayman Island — Atlanta | sat | 11:10 | 15:00 | 2h 50m | Delta Connection | search | |
| DL2512 | Grand Cayman Island — Atlanta | sat | 12:25 | 15:14 | 2h 49m | Delta Connection | search | |
| B6442 | Grand Cayman Island — Boston | sat | 10:35 | 15:34 | 3h 59m | JetBlue | search | |
| UA754 | Grand Cayman Island — Houston | sat | 12:55 | 16:08 | 3h 13m | United Express | search | |
| KX602 | Grand Cayman Island — Kingston | tue | 12:00 | 13:10 | 1h 10m | Cayman Airways | search | |
| KX4420 | Grand Cayman Island — Little Cayman | daily | 07:05 | 07:40 | 35m | Cayman Airways | search | |
| KX4624 | Grand Cayman Island — Little Cayman | daily | 14:30 | 15:05 | 35m | Cayman Airways | search | |
| KX4724 | Grand Cayman Island — Little Cayman | sat | 15:20 | 15:55 | 35m | Cayman Airways | search | |
| KX4624 | Grand Cayman Island — Little Cayman | thu | 15:49 | 16:21 | 31m | Cayman Airways | search | |
| AA367 | Grand Cayman Island — Miami | mon, tue, wed, fri, sat, sun | 14:35 | 17:20 | 1h 45m | American Eagle | from $219 | search |
| AA367 | Grand Cayman Island — Miami | daily | 15:45 | 17:30 | 1h 45m | American Eagle | from $219 | search |
| KX106 | Grand Cayman Island — Miami | mon, thu | 16:45 | 19:20 | 1h 35m | Cayman Airways | from $219 | search |
| KX106 | Grand Cayman Island — Miami | mon, thu, sun | 16:45 | 18:20 | 1h 35m | Cayman Airways | from $219 | search |
| KX106 | Grand Cayman Island — Miami | fri, sun | 17:05 | 19:40 | 1h 35m | Cayman Airways | from $219 | search |
| B6966 | Grand Cayman Island — New York | sat | 11:10 | 14:59 | 3h 49m | JetBlue | search | |
| AA1345 | Grand Cayman Island — Philadelphia | sat | 11:55 | 16:38 | 3h 43m | American Eagle | search | |
| AA1345 | Grand Cayman Island — Philadelphia | sat | 12:55 | 16:38 | 3h 43m | American Eagle | search | |
| UA309 | Grand Cayman Island — Washington | sat | 16:30 | 20:49 | 3h 19m | United Express | search | |
| UA309 | Grand Cayman Island — Washington | sat | 17:30 | 20:49 | 3h 19m | United Express | search | |