Flight schedule from Roanoke-Blacksburg Regional Airport
| Flight | Flight days | Departure | Arrival | Flight time | Airlines | Price | ||
|---|---|---|---|---|---|---|---|---|
| 2Q1260 | Roanoke — Charleston | sat | 07:45 | 08:45 | 1h 0m | Air Cargo Carriers | search | |
| UA4425 | Roanoke — Chicago | mon, tue, wed, sun | 17:35 | 18:52 | 2h 17m | United Express | search | |
| 5X1269 | Roanoke — Louisville | wed | 21:42 | 22:32 | 50m | UPS | search | |
| 5X1269 | Roanoke — Louisville | mon, tue, wed, thu, fri | 21:42 | 22:49 | 1h 7m | UPS | search | |
| 5X1269 | Roanoke — Louisville | tue | 21:42 | 22:55 | 1h 13m | UPS | search | |
| G43003 | Roanoke — Orlando | mon | 16:02 | 17:51 | 1h 49m | Allegiant Air | search | |
| AA5931 | Roanoke — Philadelphia | mon, tue, wed, thu, fri, sat | 08:15 | 09:45 | 1h 30m | American Eagle | search | |
| SY8218 | Roanoke — Richlands | fri | 13:45 | 14:45 | 1h 0m | Sun Country Airlines | search | |
| G42999 | Roanoke — Sarasota | fri | 15:06 | 17:12 | 2h 6m | Allegiant Air | search | |
| G41080 | Roanoke — Tampa | thu | 15:23 | 17:19 | 1h 56m | Allegiant Air | search | |
| G41061 | Roanoke — Tampa | thu, sun | 21:36 | 23:32 | 1h 56m | Allegiant Air | search | |
| UA4866 | Roanoke — Washington | tue, wed | 19:50 | 21:07 | 1h 17m | United Express | search | |