Flight schedule from Las Americas International Airport
| Flight | Flight days | Departure | Arrival | Flight time | Airlines | Price | ||
|---|---|---|---|---|---|---|---|---|
| DO960 | Santo Domingo — Bonaire | fri | 18:00 | 19:20 | 1h 20m | SKYhigh Dominicana | search | |
| M68512 | Santo Domingo — Comayagua | fri | 06:31 | 07:42 | 3h 10m | Amerijet International | search | |
| M68412 | Santo Domingo — Curacao | thu | 07:30 | 09:05 | 1h 35m | Amerijet International | search | |
| NK958 | Santo Domingo — Fort Lauderdale | tue, wed, thu, fri, sun | 02:52 | 05:20 | 2h 28m | Spirit Airlines | from $417 | search |
| DO781 | Santo Domingo — Georgetown | wed | 17:50 | 20:19 | 2h 29m | SKYhigh Dominicana | search | |
| DO781 | Santo Domingo — Georgetown | fri | 18:00 | 20:29 | 2h 29m | SKYhigh Dominicana | search | |
| DO781 | Santo Domingo — Georgetown | mon | 19:50 | 22:16 | 2h 26m | SKYhigh Dominicana | search | |
| DM4600 | Santo Domingo — Guatemala City | thu | 06:04 | 07:40 | 3h 36m | Arajet | search | |
| DM4600 | Santo Domingo — Guatemala City | mon | 07:15 | 08:45 | 3h 30m | Arajet | search | |
| DM4600 | Santo Domingo — Guatemala City | tue, sat | 15:54 | 17:30 | 3h 36m | Arajet | search | |
| DM3760 | Santo Domingo — Lima | tue, sun | 20:50 | 01:00 | 5h 10m | Arajet | search | |
| IB266 | Santo Domingo — Madrid | mon, wed | 16:55 | 07:20 | 8h 25m | Iberia | search | |
| IB266 | Santo Domingo — Madrid | tue | 17:30 | 07:55 | 8h 25m | Privilege Style | search | |
| IB266 | Santo Domingo — Madrid | thu, fri | 17:55 | 07:10 | 8h 15m | Privilege Style | search | |
| IB266 | Santo Domingo — Madrid | sat | 18:00 | 08:30 | 8h 30m | Iberia | search | |
| IB266 | Santo Domingo — Madrid | tue | 18:00 | 07:30 | 8h 30m | Iberia | search | |
| IB266 | Santo Domingo — Madrid | sun | 18:30 | 08:55 | 8h 25m | Privilege Style | search | |
| IB266 | Santo Domingo — Madrid | wed | 18:35 | 08:05 | 8h 30m | Privilege Style | search | |
| IB276 | Santo Domingo — Madrid | mon, wed, thu | 22:15 | 11:30 | 8h 15m | Privilege Style | search | |
| AM655 | Santo Domingo — Mexico City | tue | 11:02 | 14:05 | 5h 3m | Aeromexico Connect | from $264 | search |
| AM655 | Santo Domingo — Mexico City | mon, tue, wed, fri, sun | 11:02 | 14:05 | 5h 3m | Aeromexico | from $264 | search |
| AM655 | Santo Domingo — Mexico City | daily | 11:07 | 14:10 | 5h 3m | Aeromexico | from $264 | search |
| M68212 | Santo Domingo — Miami | tue | 11:30 | 13:50 | 2h 20m | Amerijet International | from $718 | search |
| UA1473 | Santo Domingo — New York | daily | 15:18 | 19:33 | 4h 15m | United Express | from $397 | search |
| B62510 | Santo Domingo — New York | mon, thu, fri, sat, sun | 21:42 | 01:32 | 3h 50m | JetBlue | from $397 | search |
| B62510 | Santo Domingo — New York | tue | 21:57 | 01:46 | 3h 49m | JetBlue | from $397 | search |
| B62510 | Santo Domingo — New York | wed | 21:59 | 01:48 | 3h 49m | JetBlue | from $397 | search |
| F9289 | Santo Domingo — Orlando | mon | 10:46 | 13:42 | 2h 56m | Frontier (Penny the Owl Livery) | search | |
| F9289 | Santo Domingo — Orlando | sun | 10:46 | 12:42 | 2h 56m | Frontier (Penny the Owl Livery) | search | |
| F9289 | Santo Domingo — Orlando | sat | 10:56 | 13:52 | 2h 56m | Frontier (Penny the Owl Livery) | search | |
| F9289 | Santo Domingo — Orlando | thu | 12:31 | 14:31 | 3h 0m | Frontier (Penny the Owl Livery) | search | |
| F9289 | Santo Domingo — Orlando | tue | 13:11 | 15:11 | 3h 0m | Frontier (Penny the Owl Livery) | search | |
| TX607 | Santo Domingo — Paris | tue | 21:30 | 08:45 | 6h 15m | Air Caraibes | search | |
| JY234 | Santo Domingo — Providenciales | daily | 14:00 | 15:30 | 1h 30m | interCaribbean Airways | search | |
| AA1115 | Santo Domingo — Punta Cana | sat | 17:17 | 18:14 | 57m | American Eagle | search | |
| DM4400 | Santo Domingo — San Jose | sat | 07:00 | 08:10 | 3h 10m | Arajet | search | |
| DM4460 | Santo Domingo — San Jose | wed | 09:28 | 10:38 | 3h 10m | Arajet | search | |
| DM4400 | Santo Domingo — San Jose | tue, sat | 17:53 | 19:03 | 3h 10m | Arajet | search | |
| G66208 | Santo Domingo — San Juan | tue | 14:11 | 14:51 | 39m | GlobalX | search | |
| B62538 | Santo Domingo — San Juan | mon, tue, wed, thu, fri, sun | 16:11 | 17:12 | 1h 1m | JetBlue | search | |
| B62538 | Santo Domingo — San Juan | sat | 20:15 | 21:19 | 1h 4m | JetBlue | search | |