Flight schedule from John Wayne Airport
| Flight | Flight days | Departure | Arrival | Flight time | Airlines | Price | ||
|---|---|---|---|---|---|---|---|---|
| AN50 | Santa Ana — Aspen | sun | 09:45 | 12:27 | 1h 42m | Advanced Air | search | |
| XE9400 | Santa Ana — Dallas | fri | 07:15 | 12:03 | 2h 48m | JSX | search | |
| WN3280 | Santa Ana — Dallas | sun | 14:00 | 18:55 | 2h 55m | Southwest Airlines | search | |
| AA2920 | Santa Ana — Dallas | tue, wed | 16:39 | 21:44 | 3h 5m | American Eagle | search | |
| AA3223 | Santa Ana — Dallas | mon, tue, wed, sun | 18:51 | 23:45 | 2h 54m | American Eagle | search | |
| AA3223 | Santa Ana — Dallas | mon, tue, thu, fri, sat, sun | 19:18 | 00:15 | 2h 57m | American Eagle | search | |
| AA3223 | Santa Ana — Dallas | mon, thu, fri, sat, sun | 19:23 | 00:20 | 2h 57m | American Eagle | search | |
| WN3823 | Santa Ana — Denver | tue, wed | 10:45 | 13:55 | 2h 10m | Southwest Airlines | search | |
| F94372 | Santa Ana — Denver | mon, fri, sat, sun | 11:32 | 14:52 | 2h 20m | Frontier (Penny the Owl Livery) | search | |
| F94372 | Santa Ana — Denver | thu | 12:12 | 15:35 | 2h 23m | Frontier (Penny the Owl Livery) | search | |
| WN813 | Santa Ana — Denver | sun | 12:45 | 16:00 | 2h 15m | Southwest Airlines | search | |
| UA2656 | Santa Ana — Denver | mon, wed, thu, fri, sat, sun | 18:34 | 21:52 | 2h 18m | United Express | search | |
| AN50 | Santa Ana — Hawthorne | sun | 16:00 | 16:17 | 17m | Advanced Air | search | |
| AN50 | Santa Ana — Kahului | sat | 07:00 | 10:34 | 5h 34m | Advanced Air | search | |
| WN3810 | Santa Ana — Las Vegas | tue, wed | 11:10 | 12:25 | 1h 15m | Southwest Airlines | search | |
| WN3810 | Santa Ana — Las Vegas | sat | 12:00 | 13:15 | 1h 15m | Southwest Airlines | search | |
| WN189 | Santa Ana — Las Vegas | tue, sun | 12:50 | 14:00 | 1h 10m | Southwest Airlines | search | |
| WN3810 | Santa Ana — Las Vegas | sun | 13:25 | 14:40 | 1h 15m | Southwest Airlines | search | |
| WN3810 | Santa Ana — Las Vegas | mon | 13:55 | 15:10 | 1h 15m | Southwest Airlines | search | |
| WN278 | Santa Ana — Las Vegas | tue, wed | 14:05 | 15:20 | 1h 15m | Southwest Airlines | search | |
| WN2243 | Santa Ana — Las Vegas | sat | 14:55 | 16:10 | 1h 15m | Southwest Airlines | search | |
| 5X913 | Santa Ana — Louisville | tue, wed, thu | 19:15 | 01:43 | 3h 28m | UPS | search | |
| 5X913 | Santa Ana — Louisville | mon, wed, thu, fri | 19:15 | 01:49 | 3h 34m | UPS | search | |
| JL750 | Santa Ana — Midland | wed | 12:30 | 16:21 | 1h 51m | Jet Linx Aviation | search | |
| WN278 | Santa Ana — Oakland | sat | 16:30 | 18:00 | 1h 30m | Southwest Airlines | search | |
| WN278 | Santa Ana — Oakland | sun | 16:50 | 18:20 | 1h 30m | Southwest Airlines | search | |
| WN2881 | Santa Ana — Phoenix | mon | 11:40 | 13:05 | 1h 25m | Southwest Airlines | search | |
| WN3287 | Santa Ana — Phoenix | sat | 12:45 | 14:05 | 1h 20m | Southwest Airlines | search | |
| AA457 | Santa Ana — Phoenix | mon, wed, sun | 13:27 | 14:49 | 1h 22m | American Eagle | search | |
| WN1595 | Santa Ana — Phoenix | sun | 18:25 | 19:45 | 1h 20m | Southwest Airlines | search | |
| AS712 | Santa Ana — Portland | daily | 14:12 | 16:48 | 2h 36m | Alaska Airlines | search | |
| WN4518 | Santa Ana — Sacramento | tue, wed | 06:45 | 08:35 | 1h 50m | Southwest Airlines | search | |
| WN4518 | Santa Ana — Sacramento | mon, thu, fri | 07:00 | 08:40 | 1h 40m | Southwest Airlines | search | |
| WN4518 | Santa Ana — Sacramento | sat | 07:10 | 08:45 | 1h 35m | Southwest Airlines | search | |
| WN2566 | Santa Ana — Sacramento | sun | 09:20 | 10:50 | 1h 30m | Southwest Airlines | search | |
| WN3719 | Santa Ana — Sacramento | sat | 10:45 | 12:20 | 1h 35m | Southwest Airlines | search | |
| WN4518 | Santa Ana — Sacramento | sun | 12:10 | 13:45 | 1h 35m | Southwest Airlines | search | |
| WN3719 | Santa Ana — Sacramento | mon, thu, fri, sun | 13:00 | 14:35 | 1h 35m | Southwest Airlines | search | |
| WN3720 | Santa Ana — Sacramento | mon, thu, fri, sun | 14:30 | 16:05 | 1h 35m | Southwest Airlines | search | |
| WN3720 | Santa Ana — Sacramento | tue, wed, sun | 18:50 | 20:25 | 1h 35m | Southwest Airlines | search | |
| F91366 | Santa Ana — Salt Lake City | mon | 09:40 | 12:35 | 1h 55m | Frontier (Penny the Owl Livery) | search | |
| F91366 | Santa Ana — Salt Lake City | thu, sun | 10:45 | 13:41 | 1h 56m | Frontier (Penny the Owl Livery) | search | |
| F91366 | Santa Ana — Salt Lake City | mon, fri | 10:50 | 13:46 | 1h 56m | Frontier (Penny the Owl Livery) | search | |
| UA5351 | Santa Ana — San Francisco | tue, wed | 15:45 | 17:28 | 1h 43m | United Express | search | |
| UA5351 | Santa Ana — San Francisco | thu | 15:45 | 17:30 | 1h 45m | United Express | search | |
| AS3393 | Santa Ana — San Francisco | tue, wed | 16:05 | 17:46 | 1h 41m | Alaska Airlines | search | |
| AS3465 | Santa Ana — San Francisco | wed, thu, sat | 16:39 | 18:16 | 1h 37m | Alaska Airlines | search | |
| WN3565 | Santa Ana — San Jose | mon, thu, fri, sat, sun | 08:00 | 09:25 | 1h 25m | Southwest Airlines | search | |
| WN3565 | Santa Ana — San Jose | tue, wed | 08:50 | 10:10 | 1h 20m | Southwest Airlines | search | |
| WN2805 | Santa Ana — San Jose | mon, thu, fri, sat | 20:10 | 21:30 | 1h 20m | Southwest Airlines | search | |