Cheap flights Mexico City — Santiago (MEX — SCL)

Good to know - Cheap tickets Mexico City — Santiago

Cheapest flight found $237
Minimal flight time 8h 5m
Flight distance 6614 km
Most popular airline LATAM Airlines

Airfare Mexico City – Santiago by month

Here you can find out in what months how much a ticket Mexico City – Santiago costs to buy cheap plane tickets.

Month One-way Round-trip
April 2026
February 2026
January 2026
December 2025
November 2025
October 2025
September 2025
August 2025
July 2025
June 2025
May 2025
April 2025

Remember that the optimal time for booking air tickets is 59 days before the departure date, this is the average time at which air tickets were sold at the lowest prices.

Schedule of direct flights Mexico City — Santiago

Departure Arrival Flight days Flight Airlines Flight time Airports
10:05 21:10 mon AM10 Aeromexico 8h 5m Benito Juarez International Airport — Arturo Merino Benitez Airport Select dates
10:10 21:15 tue, wed, fri, sat, sun AM10 Aeromexico 8h 5m Benito Juarez International Airport — Arturo Merino Benitez Airport Select dates
20:00 06:40 daily LA621 LATAM Airlines 8h 40m Benito Juarez International Airport — Arturo Merino Benitez Airport Select dates
20:00 06:40 mon, tue, wed, thu, fri, sat LA621 Wamos Air (20th Anniversary Sticker) 8h 40m Benito Juarez International Airport — Arturo Merino Benitez Airport Select dates
All routes

Sales of tickets from Mexico City to Santiago in the last 48 hours

2025-08-26 - 2025-09-12

Dynamics airfare Mexico City — Santiago by month for the last year

according to LowCost.Club for the last year

The airfare depends on the departure date. Our chart shows the low season prices on route Mexico City — Santiago

The graph shows that booking flights Mexico City — Santiago is best planned for October and flights Mexico City — Santiago — Mexico City in the month of March.

Flights Mexico City — Santiago

The selection of cheap flights Mexico City — Santiago

Here you can find and purchase the cheapest flights Mexico City — Santiago from $237 and Mexico City — Santiago — Mexico City from $275.

The price of the flight Mexico City — Santiago (Chile) — Mexico City from $275 (round-trip).

The average price of the flight Mexico City — Santiago (Chile) — Mexico City $862 (round-trip).

Low cost flights Mexico City — Santiago (MEX — SCL)

The distance between Mexico City and Santiago 4110 miles (or 6614 kilometres).

The time difference between Mexico City and Santiago is 2 h.

Minimal flight time from Mexico City to Santiago 8h 5m.

LowCostClub always do a comparison of airfares Mexico City — Santiago with several airlines (include Aeromexico, LATAM Airlines, Wamos Air (20th Anniversary Sticker)). They will always give you all available options so you can find the cheapest flight to Santiago. In addition, you can choose the platform where you want to place your orders. There are also special offers for air tickets Mexico City — Santiago. Last week, for instance, the cheapest round-trip prices stood at $275 while the cheapest one-way price that was available within the last week cost $237

Routes from nearby cities to Santiago

A flight from a neighbouring city can help you save money on plane tickets.

The most frequent flight to Santiago is from Leon/Guanajuato. The cheapest airfare can be purchased with a flight from Acapulco from $423. The nearest airports from Mexico City with a flight to Santiago are in Oaxaca.

Popular International routes from Mexico City

Popular routes from Santiago

If you are going to fly from Santiago, then study the popular flights. The most popular flights from Santiago:

Popular domestic routes from Mexico City

FAQ about Mexico City — Santiago

Yes, you can fly from Mexico City to Santiago. Mexico City has 4 airports (Toluca International Airport, Santa Lucia, Atizapan, Benito Juarez International Airport) for flights. Aeromexico, LATAM Airlines, Wamos Air (20th Anniversary Sticker) depart from Mexico City on mon, tue, wed, thu, fri, sat, sun. There are non-direct flights through Air France, American Airlines, Amerijet International, Arajet, Atlas Air, Avianca, Avianca Cargo, British Airways, Cargojet Airways, Copa Airlines, Delta Air Lines, DHL, Ethiopian Airlines, FedEx, Iberia, KLM Asia, LATAM Cargo, mas, SKY Airline, Turkish Airlines, UPS.

A direct flight lasts an average of 8h 5m, during which time the aircraft covers a distance of 6614 km.

The price of flights Mexico City — Santiago starts from $237.

Planes fly Mexico City — Santiago 7 times a week on the following days: mon, tue, wed, thu, fri, sat, sun

In Mexico City — Toluca International Airport, Santa Lucia, Atizapan, Benito Juarez International Airport. In Santiago — Arturo Merino Benitez Airport, Los Cerrillos.

The following flights fly between Mexico City and Santiago: AM10, AM10, LA621, LA621

High season is considered to be November and the cheapest month is October. Enter your preferred airports (or cities) and dates into the search form above to unlock the latest Mexico City — Santiago flight deals.

The following airlines have direct flights Mexico City — Santiago: Aeromexico, LATAM Airlines, Wamos Air (20th Anniversary Sticker).

All the following airlines flights Mexico City — Santiago: Aeromexico, Air France, American Airlines, Amerijet International, Arajet, Atlas Air, Avianca, Avianca Cargo, British Airways, Cargojet Airways, Copa Airlines, Delta Air Lines, DHL, Ethiopian Airlines, FedEx, Iberia, KLM Asia, LATAM Airlines, LATAM Cargo, mas, SKY Airline, Turkish Airlines, UPS, Wamos Air (20th Anniversary Sticker).

Low price calendar

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