Cheap flights Panama City — Santiago (PTY — SCL)

Good to know - Cheap tickets Panama City — Santiago

Cheapest flight found $173
Minimal flight time 5h 38m
Flight distance 4811 km
Most popular airline Copa Airlines

Airfare Panama City – Santiago by month

Here you can find out in what months how much a ticket Panama City – Santiago costs to buy cheap plane tickets.

Month One-way Round-trip
March 2026
January 2026
December 2025
November 2025
October 2025
September 2025
August 2025
July 2025
June 2025
May 2025
April 2025
March 2025

Remember that the optimal time for booking air tickets is 59 days before the departure date, this is the average time at which air tickets were sold at the lowest prices.

Schedule of direct flights Panama City — Santiago

Departure Arrival Flight days Flight Airlines Flight time Airports
11:48 19:24 daily CM395 Copa Airlines 6h 36m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
15:08 23:44 tue CM497 Copa Airlines 6h 36m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
15:08 22:44 daily CM497 Copa Airlines 6h 36m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
15:14 23:55 daily CM497 Copa Airlines 6h 41m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
15:32 00:13 daily CM171 Copa Airlines 6h 41m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
15:32 23:08 daily CM171 Copa Airlines 6h 36m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
15:35 00:11 wed CM171 Copa Airlines 6h 36m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
15:35 23:11 mon, wed, thu, fri, sat, sun CM171 Copa Airlines 6h 36m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
18:20 00:58 thu M61071 Amerijet International 5h 38m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
18:51 03:25 fri CM172 Copa Airlines 6h 34m Tocumen International Airport — Arturo Merino Benitez Airport Select dates
All routes

Sales of tickets from Panama City to Santiago in the last 48 hours

2025-10-14 one-way

2025-12-26 one-way

2025-10-14 - 2025-10-17

Dynamics airfare Panama City — Santiago by month for the last year

according to LowCost.Club for the last year

The airfare depends on the departure date. Our chart shows the low season prices on route Panama City — Santiago

The graph shows that booking flights Panama City — Santiago is best planned for August and flights Panama City — Santiago — Panama City in the month of December.

Flights Panama City — Santiago

The selection of cheap flights Panama City — Santiago

Here you can find and purchase the cheapest flights Panama City — Santiago from $173 and Panama City — Santiago — Panama City from $211.

The price of the flight Panama City — Santiago (Chile) — Panama City from $211 (round-trip).

The average price of the flight Panama City — Santiago (Chile) — Panama City $796 (round-trip).

Low cost flights Panama City — Santiago (PTY — SCL)

The distance between Panama City and Santiago 2989 miles (or 4811 kilometres).

The time difference between Panama City and Santiago is 2 h.

Minimal flight time from Panama City to Santiago 5h 38m.

LowCostClub always do a comparison of airfares Panama City — Santiago with several airlines (include Copa Airlines, Amerijet International). They will always give you all available options so you can find the cheapest flight to Santiago. In addition, you can choose the platform where you want to place your orders. There are also special offers for air tickets Panama City — Santiago. Last week, for instance, the cheapest round-trip prices stood at $211 while the cheapest one-way price that was available within the last week cost $173

Routes from nearby cities to Santiago

A flight from a neighbouring city can help you save money on plane tickets.

The most frequent flight to Santiago is from Medellin, which is the closest city to Panama City with the lowest price, from $171 per one-way.

Popular International routes from Panama City

Popular routes from Santiago

If you are going to fly from Santiago, then study the popular flights. The most popular flights from Santiago:

Popular domestic routes from Panama City

FAQ about Panama City — Santiago

Yes, they do: CM395, CM497, CM171, M61071, CM172, CM474, CM277

Yes, you can fly from Panama City to Santiago. Panama City has 2 airports (Tocumen International Airport, Marcos A. Gelabert International Airport) for flights. Copa Airlines, Amerijet International depart from Panama City on mon, tue, wed, thu, fri, sat, sun. There are non-direct flights through Air France, American Airlines, avianca, avianca Cargo, Boliviana de Aviacion, Delta Air Lines, DHL, FedEx, Iberia, KLM, LATAM Cargo, LATAM Cargo Colombia, mas, Turkish Airlines, UPS.

A direct flight lasts an average of 5h 38m, during which time the aircraft covers a distance of 4811 km.

The price of flights Panama City — Santiago starts from $173.

Planes fly Panama City — Santiago 7 times a week on the following days: mon, tue, wed, thu, fri, sat, sun

In Panama City — Tocumen International Airport, Marcos A. Gelabert International Airport. In Santiago — Arturo Merino Benitez Airport, Los Cerrillos.

The following flights fly between Panama City and Santiago: CM395, CM497, CM497, CM497, CM171, CM171, CM171, CM171, M61071, CM172, CM474, CM474, CM474, CM474, M61071, CM277

High season is considered to be September and the cheapest month is August. Enter your preferred airports (or cities) and dates into the search form above to unlock the latest Panama City — Santiago flight deals.

The following airlines have direct flights Panama City — Santiago: Copa Airlines, Amerijet International.

All the following airlines flights Panama City — Santiago: Air France, American Airlines, Amerijet International, avianca, avianca Cargo, Boliviana de Aviacion, Copa Airlines, Delta Air Lines, DHL, FedEx, Iberia, KLM, LATAM Cargo, LATAM Cargo Colombia, mas, Turkish Airlines, UPS.

Low price calendar

We use cookies and similar technologies for different purposes. Read the privacy policy. If you use the site you agree to them.