Cheap flights Panama City — Santo Domingo (PTY — SDQ)

Good to know - Cheap tickets Panama City — Santo Domingo

Cheapest flight found $139
Minimal flight time 2h 28m
Flight distance 1475 km
Most popular airline Copa Airlines

Airfare Panama City – Santo Domingo by month

Here you can find out in what months how much a ticket Panama City – Santo Domingo costs to buy cheap plane tickets.

Month One-way Round-trip
March 2026
January 2026
December 2025
November 2025
October 2025
September 2025
August 2025
July 2025
June 2025
May 2025
April 2025
March 2025

Remember that the optimal time for booking air tickets is 59 days before the departure date, this is the average time at which air tickets were sold at the lowest prices.

Schedule of direct flights Panama City — Santo Domingo

Departure Arrival Flight days Flight Airlines Flight time Airports
07:26 10:59 daily CM463 Copa Airlines 2h 33m Tocumen International Airport — Las Americas International Airport Select dates
09:37 13:05 daily CM298 Copa Airlines 2h 28m Tocumen International Airport — Las Americas International Airport Select dates
09:37 13:06 daily CM298 Copa Airlines 2h 29m Tocumen International Airport — Las Americas International Airport Select dates
09:37 13:09 daily CM298 Copa Airlines 2h 32m Tocumen International Airport — Las Americas International Airport Select dates
09:37 13:10 daily CM298 Copa Airlines 2h 33m Tocumen International Airport — Las Americas International Airport Select dates
12:44 16:17 daily CM128 Copa Airlines 2h 33m Tocumen International Airport — Las Americas International Airport Select dates
12:52 16:20 mon, tue, wed, thu, sat, sun CM128 Copa Airlines 2h 28m Tocumen International Airport — Las Americas International Airport Select dates
12:52 16:21 mon, tue, thu, sat, sun CM128 Copa Airlines 2h 29m Tocumen International Airport — Las Americas International Airport Select dates
12:52 16:24 wed, thu, fri, sat, sun CM128 Copa Airlines 2h 32m Tocumen International Airport — Las Americas International Airport Select dates
18:55 22:27 daily CM268 Copa Airlines 2h 32m Tocumen International Airport — Las Americas International Airport Select dates
All routes

Sales of tickets from Panama City to Santo Domingo in the last 48 hours

2025-07-31 - 2025-08-29

Dynamics airfare Panama City — Santo Domingo by month for the last year

according to LowCost.Club for the last year

The airfare depends on the departure date. Our chart shows the low season prices on route Panama City — Santo Domingo

The graph shows that booking flights Panama City — Santo Domingo is best planned for November and flights Panama City — Santo Domingo — Panama City in the month of May.

Flights Panama City — Santo Domingo

The selection of cheap flights Panama City — Santo Domingo

Here you can find and purchase the cheapest flights Panama City — Santo Domingo from $139 and Panama City — Santo Domingo — Panama City from $207.

The price of the flight Panama City — Santo Domingo (Dominican Republic) — Panama City from $207 (round-trip).

The average price of the flight Panama City — Santo Domingo (Dominican Republic) — Panama City $496 (round-trip).

Low cost flights Panama City — Santo Domingo (PTY — SDQ)

The distance between Panama City and Santo Domingo 917 miles (or 1475 kilometres).

The time difference between Panama City and Santo Domingo is 1 h.

Minimal flight time from Panama City to Santo Domingo 2h 28m.

LowCostClub always do a comparison of airfares Panama City — Santo Domingo with several airlines (include Copa Airlines). They will always give you all available options so you can find the cheapest flight to Santo Domingo. In addition, you can choose the platform where you want to place your orders. There are also special offers for air tickets Panama City — Santo Domingo. Last week, for instance, the cheapest round-trip prices stood at $207 while the cheapest one-way price that was available within the last week cost $139

Routes from nearby cities to Santo Domingo

A flight from a neighbouring city can help you save money on plane tickets.

Most often, departures to Santo Domingo are from San Jose, this is the cheapest flight from $120. The nearest airports from Panama City with a flight to Santo Domingo are located in Barranquilla.

Popular International routes from Panama City

Popular routes from Santo Domingo

If you are going to fly from Santo Domingo, then study the popular flights. The most popular flights from Santo Domingo:

Popular domestic routes from Panama City

FAQ about Panama City — Santo Domingo

Yes, they do: CM463, CM298, CM128, CM268, CM107

Yes, you can fly from Panama City to Santo Domingo. Panama City has 2 airports (Tocumen International Airport, Marcos A. Gelabert International Airport) for flights. Copa Airlines departs from Panama City on mon, tue, wed, thu, fri, sat, sun. There are non-direct flights through Aeromexico, Air Europa, American Airlines, Amerijet International, Avianca, Avianca Cargo, Cargojet Airways, Condor, Delta Air Lines, FedEx, Iberia, LATAM Cargo, Privilege Style, United Airlines, UPS, Wingo Panama.

A direct flight lasts an average of 2h 28m, during which time the aircraft covers a distance of 1475 km.

The price of flights Panama City — Santo Domingo starts from $139.

Planes fly Panama City — Santo Domingo 7 times a week on the following days: mon, tue, wed, thu, fri, sat, sun

In Panama City — Tocumen International Airport, Marcos A. Gelabert International Airport. In Santo Domingo — Santo Domingo Herrera, Las Americas International Airport.

The following flights fly between Panama City and Santo Domingo: CM463, CM298, CM298, CM298, CM298, CM128, CM128, CM128, CM128, CM268, CM268, CM107

High season is considered to be January and the cheapest month is November. Enter your preferred airports (or cities) and dates into the search form above to unlock the latest Panama City — Santo Domingo flight deals.

Only one airline operates a direct flight Panama City — Santo Domingo: Copa Airlines.

All the following airlines flights Panama City — Santo Domingo: Aeromexico, Air Europa, American Airlines, Amerijet International, Avianca, Avianca Cargo, Cargojet Airways, Condor, Copa Airlines, Delta Air Lines, FedEx, Iberia, LATAM Cargo, Privilege Style, United Airlines, UPS, Wingo Panama.

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