Cheap flights Santa Cruz — Panama City (SRZ — PTY)

Good to know - Cheap tickets Santa Cruz — Panama City

Cheapest flight found $211
Minimal flight time 4h 40m
Flight distance 3477 km
Most popular airline Copa Airlines

Airfare Santa Cruz – Panama City by month

Here you can find out in what months how much a ticket Santa Cruz – Panama City costs to buy cheap plane tickets.

Month One-way Round-trip
June 2026
January 2026
December 2025
November 2025
October 2025
September 2025
August 2025
July 2025
June 2025
May 2025
April 2025
March 2025

Remember that the optimal time for booking air tickets is 59 days before the departure date, this is the average time at which air tickets were sold at the lowest prices.

Schedule of direct flights Santa Cruz — Panama City

Departure Arrival Flight days Flight Airlines Flight time Airports
01:09 05:04 mon, tue CM126 Copa Airlines 4h 55m Viru Viru International Airport — Tocumen International Airport Select dates
09:30 13:10 tue OB760 Boliviana de Aviacion 4h 40m Viru Viru International Airport — Tocumen International Airport Select dates
11:40 15:35 mon, tue, thu, sat CM220 Copa Airlines 4h 55m Viru Viru International Airport — Tocumen International Airport Select dates
11:44 15:35 mon, thu, sat CM220 Copa Airlines 4h 51m Viru Viru International Airport — Tocumen International Airport Select dates
All routes

Popular airlines flying Santa Cruz — Panama City

Flight Santa Cruz – Panama City is served by 2 airlines.  2 airlines operate direct flights.


Airlines with direct flights


Other airlines flying with transfers

Sales of tickets from Santa Cruz to Panama City in the last 48 hours

2025-12-29 one-way

Flights Santa Cruz — Panama City

The selection of cheap flights Santa Cruz — Panama City

Here you can find and purchase the cheapest flights Santa Cruz — Panama City from $211 and Santa Cruz — Panama City — Santa Cruz from $347.

The price of the flight Santa Cruz — Panama City (Panama) — Santa Cruz from $347 (round-trip).

The average price of the flight Santa Cruz — Panama City (Panama) — Santa Cruz $703 (round-trip).

Low cost flights Santa Cruz — Panama City (SRZ — PTY)

The distance between Santa Cruz and Panama City 2161 miles (or 3477 kilometres).

The time difference between Santa Cruz and Panama City is 1 h.

Minimal flight time from Santa Cruz to Panama City 4h 40m.

LowCostClub always do a comparison of airfares Santa Cruz — Panama City with several airlines (include Copa Airlines, Boliviana de Aviacion). They will always give you all available options so you can find the cheapest flight to Panama City. In addition, you can choose the platform where you want to place your orders. There are also special offers for air tickets Santa Cruz — Panama City. Last week, for instance, the cheapest round-trip prices stood at $347 while the cheapest one-way price that was available within the last week cost $211

Routes from nearby cities to Panama City

A flight from a neighbouring city can help you save money on plane tickets.

Most often, departures to Panama City are from La Paz, this is the cheapest flight from $184. The nearest airports from Santa Cruz with a flight to Panama City are located in Trinidad.

Popular International routes from Santa Cruz

Popular routes from Panama City

If you are going to fly from Panama City, then study the popular flights. The most popular flights from Panama City:

Popular domestic routes from Santa Cruz

FAQ about Santa Cruz — Panama City

Yes, you can fly from Santa Cruz to Panama City. Santa Cruz has 2 airports (El Trompillo, Viru Viru International Airport) for flights. Copa Airlines, Boliviana de Aviacion depart from Santa Cruz on mon, tue, thu, sat. There are non-direct flights through Air Europa, avianca.

A direct flight lasts an average of 4h 40m, during which time the aircraft covers a distance of 3477 km.

The price of flights Santa Cruz — Panama City starts from $211.

Planes fly Santa Cruz — Panama City 4 times a week on the following days: mon, tue, thu, sat

In Santa Cruz — El Trompillo, Viru Viru International Airport. In Panama City — Tocumen International Airport, Marcos A. Gelabert International Airport.

The following flights fly between Santa Cruz and Panama City: CM126, OB760, CM220, CM220

High season is considered to be and the cheapest month is . Enter your preferred airports (or cities) and dates into the search form above to unlock the latest Santa Cruz — Panama City flight deals.

The following airlines have direct flights Santa Cruz — Panama City: Copa Airlines, Boliviana de Aviacion.

All the following airlines flights Santa Cruz — Panama City: Air Europa, avianca, Boliviana de Aviacion, Copa Airlines.

Low price calendar

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