Using the online timetable is an easy way to look at all the direct flights Des Moines — Chicago
142 flights in a week
Departure and arrival times are local (Des Moines and Chicago)
| Departure | Arrival | Flight days | Flight | Airlines | Flight time | Airports | |
|---|---|---|---|---|---|---|---|
| 05:00 | 06:24 | mon, thu, fri, sun | AA449 | American Airlines | 1h 24m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 05:00 | 06:25 | wed | AA449 | American Airlines | 1h 25m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 05:45 | 07:12 | sat, sun | AA4451 | American Airlines | 1h 27m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 05:45 | 07:16 | sat | AA4451 | American Airlines | 1h 31m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 06:00 | 07:27 | sun | AA4451 | American Airlines | 1h 27m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 06:00 | 07:29 | mon | AA6416 | American Airlines | 1h 29m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 06:00 | 07:24 | tue, wed, fri, sat | AA449 | American Airlines | 1h 24m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 06:05 | 07:29 | tue | AA449 | American Airlines | 1h 24m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 06:24 | 08:05 | mon, fri | UA4677 | United Airlines | 1h 41m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 06:25 | 08:05 | tue, wed, fri | UA5458 | United Airlines | 1h 40m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 06:25 | 08:05 | thu | UA5458 | SkyWest Airlines | 1h 40m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 07:00 | 08:20 | sat | AA9867 | American Airlines | 1h 20m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 07:20 | 09:06 | sat | AA4519 | American Airlines | 1h 46m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 07:24 | 09:10 | mon, tue, wed, thu, fri, sun | AA4519 | American Airlines | 1h 46m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 07:26 | 08:55 | sat | AA449 | American Airlines | 1h 29m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 07:30 | 09:08 | tue, sun | AA4519 | American Airlines | 1h 38m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 08:00 | 09:32 | daily | UA1363 | United Airlines | 1h 32m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 08:07 | 09:38 | mon, thu | UA1363 | United Airlines | 1h 31m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 08:10 | 09:38 | daily | UA1363 | United Airlines | 1h 28m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 09:00 | 10:25 | sat | AA9867 | American Airlines | 1h 25m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 09:30 | 10:33 | sun | American Airlines | 1h 3m | Des Moines International Airport — O'Hare International Airport | Select dates | |
| 09:37 | 11:09 | thu, sat, sun | AA6260 | American Airlines | 1h 32m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 09:54 | 11:22 | sat | AA6264 | American Airlines | 1h 28m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 11:12 | 12:40 | thu | UA2306 | United Airlines | 1h 28m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 11:16 | 12:48 | mon, tue, wed, thu, fri | UA2306 | United Airlines | 1h 32m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 11:20 | 12:55 | sat | UA4396 | United Airlines | 1h 35m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 11:25 | 13:00 | sun | UA5876 | United Airlines | 1h 35m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 11:26 | 13:02 | sat, sun | UA3467 | United Airlines | 1h 36m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 11:35 | 13:13 | sat, sun | UA4469 | United Airlines | 1h 38m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 11:53 | 13:20 | mon, wed | AA3361 | American Airlines | 1h 27m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 11:56 | 13:23 | wed, thu, fri, sat | AA6061 | American Airlines | 1h 27m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 12:45 | 13:45 | mon | UA5143 | United Airlines | 1h 0m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 13:57 | 15:27 | sat | AA6480 | American Airlines | 1h 30m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 13:58 | 15:23 | mon, tue, fri | AA6480 | American Airlines | 1h 25m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 14:08 | 15:38 | tue | AA6480 | SkyWest Airlines | 1h 30m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 14:12 | 15:44 | mon, wed, fri, sun | AA6519 | American Airlines | 1h 32m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 14:20 | 15:49 | mon, wed, thu | AA6285 | American Airlines | 1h 29m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:08 | 16:40 | tue, sat | AA6519 | American Airlines | 1h 32m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:15 | 16:45 | thu | UA1741 | United Airlines | 1h 30m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:23 | 16:53 | tue | AA4923 | American Airlines | 1h 30m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:25 | 16:55 | mon, fri | UA1741 | United Airlines | 1h 30m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:28 | 16:58 | tue, wed, sun | UA1741 | United Airlines | 1h 30m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:34 | 17:07 | sun | UA3574 | United Airlines | 1h 33m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:34 | 17:05 | mon, tue, wed | UA1568 | United Airlines | 1h 31m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:35 | 17:10 | sat, sun | UA3429 | United Airlines | 1h 35m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:38 | 17:10 | mon, tue, wed, thu, fri | UA1568 | United Airlines | 1h 32m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 15:42 | 17:10 | fri | UA1568 | United Airlines | 1h 28m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 16:00 | 17:33 | fri, sun | AA6039 | American Airlines | 1h 33m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 16:04 | 17:33 | mon, wed, thu, fri, sat, sun | AA6264 | American Airlines | 1h 29m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 17:58 | 19:31 | tue, wed, fri | AA6536 | American Airlines | 1h 33m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 18:00 | 19:35 | daily | AA6039 | American Airlines | 1h 35m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 18:13 | 19:40 | mon, tue, thu, sun | AA3967 | American Airlines | 1h 27m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 18:14 | 19:45 | fri, sun | AA4704 | American Airlines | 1h 31m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 18:16 | 19:46 | wed, thu, sat | AA4923 | American Airlines | 1h 30m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 18:45 | 20:20 | wed, thu, sun | UA3586 | United Airlines | 1h 35m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 18:50 | 20:25 | fri, sat, sun | UA5244 | United Airlines | 1h 35m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 19:30 | 21:00 | sun | UA5142 | United Airlines | 1h 30m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 21:11 | 21:59 | fri | FX1387 | FedEx | 48m | Des Moines International Airport — O'Hare International Airport | Select dates |
| 23:15 | 00:37 | thu | UA3045 | United Airlines | 1h 22m | Des Moines International Airport — O'Hare International Airport | Select dates |