Using the online timetable is an easy way to look at all the direct flights Panama City — Santa Cruz
36 flights in a week
Departure and arrival times are local (Panama City and Santa Cruz)
| Departure | Arrival | Flight days | Flight | Airlines | Flight time | Airports | |
|---|---|---|---|---|---|---|---|
| 16:17 | 22:19 | tue, wed, thu, sat, sun | CM127 | Copa Airlines | 5h 2m | Tocumen International Airport — Viru Viru International Airport | Select dates |
| 16:25 | 22:25 | daily | CM127 | Copa Airlines | 5h 0m | Tocumen International Airport — Viru Viru International Airport | Select dates |
| 16:40 | 22:40 | tue, thu, fri, sat, sun | CM127 | Copa Airlines | 5h 0m | Tocumen International Airport — Viru Viru International Airport | Select dates |
| 21:43 | 03:39 | daily | CM221 | Copa Airlines | 4h 56m | Tocumen International Airport — Viru Viru International Airport | Select dates |
| 21:43 | 03:37 | tue, thu, fri, sat | CM221 | Copa Airlines | 4h 54m | Tocumen International Airport — Viru Viru International Airport | Select dates |
| 21:43 | 03:36 | mon, tue, wed, thu, sat | CM221 | Copa Airlines | 4h 53m | Tocumen International Airport — Viru Viru International Airport | Select dates |
| 23:40 | 05:20 | tue, wed, sat | OB769 | Boliviana de Aviacion | 4h 40m | Tocumen International Airport — Viru Viru International Airport | Select dates |